182k views
2 votes
Which method is best suited for qualitative analysis of DNA, such as mutational analysis, where many samples are compared simultaneously?

User Zeeba
by
7.2k points

1 Answer

4 votes

Final answer:

For qualitative analysis of DNA, microarray analysis and Next-generation Sequencing (NGS) are the best methods for comparing multiple samples simultaneously. UV spectroscopy can also be used, but it may not be as efficient.

Step-by-step explanation:

For qualitative analysis of DNA, such as mutational analysis, where many samples are compared simultaneously, the best method is microarray analysis. Microarray analysis allows for the comparison of gene-expression patterns between different cell types. It is particularly useful when studying the differences in gene expression between infected and uninfected cells or healthy and cancerous cells.

Another suitable method is Next-generation Sequencing (NGS). NGS is a group of automated techniques used for rapid DNA sequencing. It can generate sequences of hundreds of thousands or millions of short DNA fragments in a single day, allowing for efficient analysis and comparison of multiple samples.

UV spectroscopy can also be used, but it requires large volumes of DNA and may not be as efficient for comparing multiple samples simultaneously.

User Nheinrich
by
7.5k points