Final answer:
The Mystic Massacre occurred during the Pequot War, where an assault on a Pequot stronghold by English settlers and their Native allies led to a devastating fire and massacre.
Step-by-step explanation:
The Mystic Massacre took place during the Pequot War, a conflict that arose when new colonists seeking land encroached on Pequot territories. One of the key episodes was the violent attack by the English settlers and their Native American allies on the Pequot fort at Mystic, Connecticut. In a tragic turn of events, the Pequot stronghold was set aflame at night, leading to the death of hundreds of Pequot inhabitants. The Treaty of Hartford terminated the Pequot War, leading to the enslavement and displacement of the surviving Pequot people. The Pequot War, as a precursor to Metacom's War, played a pivotal role in the erosion of relations between the Native Americans and European settlers.