Final answer:
The most common location where action potentials originate is the axon hillock, which is located at the base of the cell body.
Step-by-step explanation:
The most common location where action potentials originate is the axon hillock. The axon hillock is located at the base of the soma (cell body) and is where signals from multiple synapses on the dendrites are integrated and initiate an action potential. Once the action potential is generated at the axon hillock, it travels down the axon and can be transmitted to another cell.