Final answer:
Claire describes a significant transformation of individuals that has led to a shocking response. They have changed from their previous state into something completely different, making them feel 'alien' or 'outside' to observers.
Step-by-step explanation:
The dialogue provided appears to be from a work of literature or a script, in which a character named Claire is discussing an event or a transformation that has left everyone shocked. The key understanding from Claire's explanation is that some individuals or characters have undergone a significant change, moving away from what they previously were to something entirely different, essentially becoming 'alien' or 'outside' of their former selves. This fundamental change is what has caused the shocking reaction amongst others.