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The biochemical defect in phenylketonuria (PKU) is a functional deficiency of the liver enzyme phenylalanine hydroxylase, which catalyzes the para-hydroxylation of phenylalanine to yield what amino acid?

1: Threonine
2: Alanine
3: Methionine
4: Tyrosine

User Ignis
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Final answer:

The biochemical defect in phenylketonuria (PKU) is a functional deficiency of the liver enzyme phenylalanine hydroxylase, which catalyzes the para-hydroxylation of phenylalanine to yield tyrosine.

Step-by-step explanation:

The biochemical defect in phenylketonuria (PKU) is a functional deficiency of the liver enzyme phenylalanine hydroxylase, which catalyzes the para-hydroxylation of phenylalanine to yield the amino acid tyrosine.

User Sepupic
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