Final answer:
Thalassemia, a genetic disease that affects hemoglobin production, can negatively impact muscle tissue by reducing oxygen supply and causing symptoms like weakness and fatigue.
Step-by-step explanation:
Thalassemia is a genetic disease that causes abnormal hemoglobin production. As a result, individuals with thalassemia have lower-than-normal levels of hemoglobin, which reduces the blood's ability to deliver oxygen to tissues. This can affect muscle tissue by impairing oxygen supply, leading to symptoms such as muscle weakness, fatigue, and exercise intolerance