Final answer:
The lab technique that uses particle size differences to separate mixture components is called filtration. It isolates solids from fluids through a medium that allows only the fluid to pass, leaving solids behind.
Step-by-step explanation:
The basic lab technique that involves the separation of a mixture's components through the differences in particle size is filtration. Filtration is a mechanical, physical or biological operation that separates solids from fluids (liquids or gases) by adding a medium through which only the fluid can pass. The substance that passes through is known as the filtrate. This process can separate a heterogeneous mixture, such as sand and water, where the water is able to pass through a filter paper, leaving behind the sand particles.