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What is thermigenin and how does it promote heat production by brown dat tissue of human babies or hibernating animals?

User Yukulelix
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Final answer:

Thermogenin, found in the mitochondria of brown adipose tissue, facilitates heat production by uncoupling oxidative phosphorylation, leading to the release of energy as heat instead of ATP synthesis. This mechanism is crucial for newborn humans and hibernating animals, as it helps regulate body temperature without shivering.

Step-by-step explanation:

Thermogenin, also known as uncoupling protein 1 (UCP1), is an integral membrane protein found in the mitochondria of brown adipose tissue (brown fat) that promotes heat production through nonshivering thermogenesis. This special type of fat contains a higher number of mitochondria, which are the powerhouses of the cell, packed with thermogenin. Newborn human babies and hibernating animals have an abundance of brown fat that helps them regulate body temperature in cold environments.



When exposed to cold temperatures, brown fat activates thermogenin, which uncouples oxidative phosphorylation. This means that instead of using energy from the electron transport chain to produce adenosine triphosphate (ATP), which is normally used for energy, it allows the energy to be released as heat. By so doing, thermogenin helps maintain a warm body temperature. The breakdown of brown fat is automatic upon cold exposure, thereby serving as a crucial heat regulator, especially in newborns and hibernating animals.



In newborns, brown fat is essential due to their higher surface area to mass ratio, which makes them lose heat more rapidly. They possess brown fat deposits around arteries warming the circulating blood. For animals in hibernation, this brown fat reserves are crucial for surviving prolonged periods of cold without the need for constant feeding or shivering.

User Mtnkodiak
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