Final answer:
Metabolic engineering was used to prove that Superoxide Dismutase (SOD) helps extend the lifespan of mice by reducing oxidative damage caused by reactive oxygen species and superoxide radicals.
Step-by-step explanation:
Metabolic engineering was used to prove that Superoxide Dismutase (SOD) helps to extend the lifespan of mice. Research has shown that reducing oxidative damage, which is caused by reactive oxygen species and superoxide radicals, can result in a longer lifespan in certain organisms. Superoxide dismutases, such as SOD, are enzymes that protect cells against superoxide radicals and prevent the formation of other active oxygen species. By manipulating the expression and activity of SOD in mice through metabolic engineering, scientists were able to demonstrate that increased SOD activity can extend the lifespan of mice by reducing oxidative damage.