Final answer:
The primary concern of the Anti-Federalists was a fear of excessive power in the new government and lack of protection for individual liberties.
Step-by-step explanation:
The primary concern of the Anti-Federalists in relation to the proposed Constitution was a fear that the new government would have too much power and the people too little power. The Anti-Federalists believed that the Constitution would concentrate too much power in the hands of the federal government, similar to the way the British government had done in the past. They also feared that the new government would not adequately protect individual liberties and would not include a bill of rights. These concerns led the Anti-Federalists to advocate for a weaker central government and stronger state governments.