Final answer:
To safely make a left turn from a two-way road into a four-lane highway, enter the right lane to the left of the center line and then change lanes only when it's safe.
Step-by-step explanation:
When you make a left turn from a two-way road into a four-lane highway, you must enter the right lane, to the left of the center line. This is typically the safest way to integrate into highway traffic, allowing other vehicles to pass on the left. Once you are in the right lane and when traffic permits, you may move to a different lane if necessary. It is important to remember that traffic often moves in a straight line and making a left turn requires careful attention to the motion of oncoming traffic, as well as vehicles on the highway itself.