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A 45 y/o, 200lb patient is struggling with severe dermatitis and the provider wants to potentially start a biologic. Which medication would you recommend?

1) Protopic (tacrolimus)
2) Humira (adalimumab)
3) Stelara (ustekinumab)
4) Dupixent (dupilumab)

1 Answer

5 votes

Final answer:

For a patient with severe dermatitis, Dupixent (dupilumab) is often recommended for its effectiveness in targeting the underlying cause of inflammation in moderate-to-severe atopic dermatitis. However, the final choice should be based on a thorough medical evaluation by a healthcare provider.

Step-by-step explanation:

When considering a biologic medication for a 45-year-old 200lb patient struggling with severe dermatitis, it is essential to determine the specific type of dermatitis and evaluate the patient's overall health, including any other medical conditions they may have. Among the options listed:

  • Protopic (tacrolimus) is a topical calcineurin inhibitor used for atopic dermatitis. It's generally not classified as a biologic but can be used for dermatitis on sensitive areas.
  • Humira (adalimumab) is a biologic that can be used for conditions like psoriatic arthritis, chronic plaque psoriasis, and other autoimmune diseases.
  • Stelara (ustekinumab) is a biologic that targets interleukins involved in the inflammatory process and is used for conditions like plaque psoriasis and psoriatic arthritis.
  • Dupixent (dupilumab) is specifically designed for moderate-to-severe atopic dermatitis. It targets the underlying cause of the inflammation and is often recommended for long-term treatment of dermatitis especially when it's not controlled by other treatments.

Based on current guidelines, Dupixent (dupilumab) could potentially be the best recommendation for severe cases of dermatitis, subject to the healthcare provider's assessment and confirmation that the patient has atopic dermatitis. However, personal medical history, potential drug interactions, and the patient's specific medical condition should always be taken into account before starting any new medication.

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