Final answer:
Mekinist (trametinib) is the medication that does not have an FDA approved indication for renal cell carcinoma. Other listed drugs like Cabometyx, Afinitor, Sutent, and Nexavar are approved for this condition.
Step-by-step explanation:
The question is regarding which medication does not have a Food and Drug Administration (FDA) approved indication for the treatment of renal cell carcinoma. The answer is Mekinist (trametinib), as it is not approved by the FDA for this specific indication. On the other hand, Cabometyx (cabozantinib), Afinitor (everolimus), Sutent (sunitinib), and Nexavar (sorafenib) are all medications that have been approved by the FDA to treat renal cell carcinoma.