Final answer:
Rituxin (rituximab) is the biologic drug among those listed that increases the risk of neutropenia, a condition where the neutrophil count is abnormally low, compromising the immune system's ability to fight off infections.
Step-by-step explanation:
The question asks which among the listed biologic drugs increases the risk of neutropenia. Neutropenia is a condition characterized by an abnormally low count of neutrophils, a type of white blood cell that helps the body fight off infections. Of the biologic drugs listed, Rituxin (rituximab) is known to increase the risk of neutropenia. Rituximab is a monoclonal antibody that targets the CD20 protein found on the surface of B-lymphocytes, leading to their destruction. While this action is beneficial for treating conditions such as Non-Hodgkin's lymphoma and chronic lymphocytic leukemia, it can also result in decreased immunity, particularly manifested by neutropenia, hence increasing the risk of infections.