Final answer:
Small fiber neuropathy affects small nerve fibers and is usually associated with conditions like diabetes, while large fiber neuropathy affects larger nerve fibers and is often hereditary.
Step-by-step explanation:
Small fiber neuropathy and large fiber neuropathy are two types of peripheral neuropathies that affect different types of nerve fibers. Small fiber neuropathy primarily affects the small nerve fibers that control pain and temperature sensation, while large fiber neuropathy affects the larger nerve fibers responsible for vibration and proprioception.
A common example of small fiber neuropathy is diabetic neuropathy, where the small fibers are damaged due to high blood sugar levels. This can lead to symptoms such as numbness, tingling, and burning pain in the hands and feet.
A common example of large fiber neuropathy is Charcot-Marie-Tooth disease, a hereditary condition that affects the larger fibers and can lead to muscle weakness and loss of coordination.
Acetylcholine is degraded after binding to its receptor to ensure proper termination of the signal and prevent continuous muscle contractions.