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Reticulocytes complete their development into ________ in the circulation.

A) neutrophils
B) megakaryocytes
C) thrombocytes
D) macrophages
E) erythrocytes

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Final answer:

Reticulocytes mature into erythrocytes, which are red blood cells that lack a nucleus and contain hemoglobin. Myeloid stem cells are the precursors to multiple blood components including erythrocytes, platelets, and various types of leukocytes. Macrophages, which come from monocytes, are responsible for removing aged and damaged erythrocytes from circulation.

Step-by-step explanation:

Reticulocytes complete their development into erythrocytes in the circulation. This is the correct answer to the question posed. Reticulocytes are immature red blood cells (RBCs) that have been released from the bone marrow into the bloodstream. Here, they undergo final stages of maturation, typically within 1 to 2 days, before becoming fully mature erythrocytes, which lack a nucleus and are packed with hemoglobin, the oxygen-carrying protein. When considering hematopoiesis, myeloid stem cells give rise to a variety of formed elements including erythrocytes, megakaryocytes (which produce platelets, also known as thrombocytes), and myeloblast lineage cells that develop into monocytes and three forms of granular leukocytes (neutrophils, eosinophils, and basophils). It's important to note that macrophages arise from monocytes and play a role in phagocytizing aging and damaged erythrocytes as part of the body's way of recycling components like iron and globin proteins.

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