Final answer:
Under TCPS 2, individuals in vulnerable circumstances can participate in research with ethical considerations and safeguards in place.
Step-by-step explanation:
Under TCPS 2 (Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans), individuals who are in vulnerable circumstances can participate in research, but special provisions are put in place to protect their rights and well-being. TCPS 2 requires that participation be voluntary, the selection of research subjects be fair, confidentiality be preserved, and risks to participants be minimized. The study should also yield important results for society.
Historically, vulnerable populations have been exploited and coerced in research. An infamous example is the Tuskegee syphilis study, where Black men were misled and denied treatment. However, ethical guidelines now prioritize the protection and informed consent of research participants. Researchers must ensure that participants are fully informed and that their safety is guaranteed.
Overall, TCPS 2 allows individuals who are in vulnerable circumstances to participate in research, but with strict ethical considerations and safeguards in place.