Question

When protein kinase A is activated via the sympathetic nervous system, what are the 3 places of control is has in a myocyte?

Answer 1

Protein kinase A, when activated in a myocyte, controls glycogen degradation, glycogen synthesis, and cellular metabolism.

Step-by-step explanation:

When protein kinase A is activated via the sympathetic nervous system in a myocyte, it has three places of control:

1. Glycogen degradation: Protein kinase A phosphorylates and activates the enzyme glycogen phosphorylase kinase, which then activates glycogen phosphorylase. This enzyme promotes the breakdown of glycogen into glucose.
2. Glycogen synthesis: Protein kinase A phosphorylates and inhibits the enzyme glycogen synthase, which prevents the formation of glycogen from glucose.
3. Cellular metabolism: Protein kinase A phosphorylates and activates multiple enzymes involved in cellular metabolism, leading to various cell-specific responses.