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What are the steps of synaptic transmission in the adrenergic nerve terminal?

1 Answer

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Final answer:

Synaptic transmission in the adrenergic nerve terminal involves the release of neurotransmitters from the presynaptic neuron to the postsynaptic neuron. The neurotransmitters bind to receptors on the postsynaptic membrane, triggering a change in membrane potential.

Step-by-step explanation:

Synaptic transmission in the adrenergic nerve terminal involves several steps:

  1. When an action potential reaches the axon terminals, voltage-gated Ca²+ channels open in the membrane of the synaptic end bulb. Ca²+ ions enter the end bulb and bind to proteins on the outer surface of neurotransmitter vesicles.
  2. The Ca²+ ions facilitate the merging of the vesicle with the presynaptic membrane, resulting in the release of neurotransmitters through exocytosis into the synaptic cleft.
  3. The neurotransmitters diffuse across the synaptic cleft and bind to ligand-gated ion channels on the postsynaptic membrane.
  4. The binding of neurotransmitters to the ligand-gated ion channels triggers a change in the postsynaptic membrane potential, either depolarization or hyperpolarization, depending on the specific neurotransmitter and receptor.