Final answer:
Approximately 620,000 Americans died as a result of the American Civil War, with losses from both the Union and Confederate forces.
Step-by-step explanation:
About how many Americans (Union and Confederate) died as a result of the Civil War? During the American Civil War from 1861 to 1865, approximately 620,000 Americans lost their lives with about 220,000 men killed or died of wounds, and an additional 400,000 from infectious diseases.
This massive loss of life included soldiers from both the Union and the Confederacy: the South lost at least 260,000 people,
while the North lost over 360,000, with collectively around 472,000 people suffering from battle-related wounds.