Final answer:
Sodium (Na+) and potassium (K+) ions are crucial in generating the electrical polarity of a nerve, creating the membrane potential necessary for nerve impulse transmission.
Step-by-step explanation:
The two chemicals that are instrumental in generating the electrical polarity of a nerve are sodium (Na+) and potassium (K+) ions. These ions maintain different concentrations inside and outside the nerve cell, which creates an electrochemical gradient across the neuronal membrane. The difference in concentration of these ions is crucial for the development of the membrane potential, which is approximately -70 mV in a resting nerve cell. During the action potential, sodium ion channels open, allowing Na+ ions to rush into the cell, which reverses the charge inside and initiates an electric current along the axon.
The altered distribution of these positively charged ions changes the membrane potential from negative to positive, creating the conditions necessary for nerve impulse transmission. This process is also called depolarization, which is swiftly followed by repolarization, resetting the membrane potential back to its resting state.