Question

Describe the structure and function of G-protein coupled receptors and their importance as targets for drug discovery.

a) Transmit signals across the cell membrane
b) Store genetic information
c) Facilitate protein synthesis
d) Maintain cell structure

Answer 1

G-protein coupled receptors (GPCRs) transmit signals across the cell membrane by interacting with a ligand and associated G-protein. They are important targets for drug discovery due to their involvement in various physiological processes.

Step-by-step explanation:

G-protein coupled receptors (GPCRs) are a type of receptor that transmit signals across the cell membrane. These receptors have seven transmembrane domains and bind to a ligand, which activates an associated G-protein. The activated G-protein can then interact with other proteins in the cell, such as ion channels or enzymes, to transmit the signal and initiate cellular responses.

GPCRs are of great importance in drug discovery because they are involved in many physiological processes and signaling pathways. By targeting GPCRs with specific drugs, researchers can modulate these pathways and potentially treat various diseases and disorders.