Final answer:
NF-1 and NF-2 are two genetic conditions that affect the nervous system. They differ in the genes involved and the types of tumors that develop.
Step-by-step explanation:
Neurofibromatosis Type 1 (NF-1) and Neurofibromatosis Type 2 (NF-2) are two different genetic conditions that affect the nervous system. While they both cause the formation of tumors, there are several distinguishing characteristics between the two.
A major difference is the genes involved. NF-1 is caused by a mutation in the NF1 gene on chromosome 17, while NF-2 is caused by a mutation in the NF2 gene on chromosome 22.
Another difference is the types of tumors that develop. In NF-1, tumors known as neurofibromas can develop on or under the skin, as well as in other parts of the body. In contrast, NF-2 primarily causes the growth of schwannomas, which are tumors that develop on the nerves responsible for hearing and balance.