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What are the distinguishing characteristics of NF-1 from NF-2?

User OverStack
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Final answer:

NF-1 and NF-2 are two genetic conditions that affect the nervous system. They differ in the genes involved and the types of tumors that develop.

Step-by-step explanation:

Neurofibromatosis Type 1 (NF-1) and Neurofibromatosis Type 2 (NF-2) are two different genetic conditions that affect the nervous system. While they both cause the formation of tumors, there are several distinguishing characteristics between the two.

A major difference is the genes involved. NF-1 is caused by a mutation in the NF1 gene on chromosome 17, while NF-2 is caused by a mutation in the NF2 gene on chromosome 22.

Another difference is the types of tumors that develop. In NF-1, tumors known as neurofibromas can develop on or under the skin, as well as in other parts of the body. In contrast, NF-2 primarily causes the growth of schwannomas, which are tumors that develop on the nerves responsible for hearing and balance.

User Mantono
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