Final answer:
The development of the US economy creates a separation between certain regions/states through economic disparities, cultural divisions, and political conflicts. Slavery played a significant part in all of these divisions.
Step-by-step explanation:
Three ways that the development of the US economy creates a separation between certain regions/states are through economic disparities, cultural divisions, and political conflicts. Slavery played a significant part in all of these divisions. The Southern economy heavily relied on slavery for agricultural production, while the North did not benefit economically from slavery. This economic disparity, along with cultural and political differences, contributed to the separation between regions.