Final answer:
Nonsteroidal anti-inflammatory drugs (NSAIDs), including aspirin, ibuprofen, and naproxen, are the most commonly prescribed medications for inflammation and are available over the counter.
Step-by-step explanation:
The most commonly prescribed medication for inflammation is nonsteroidal anti-inflammatory drugs (NSAIDs). These drugs are distinct from steroids as they do not have the wide range of effects that steroids possess and have been primarily popular since their distinction was made in the 1960s. The most well-known NSAIDs include aspirin, ibuprofen, and naproxen, which are available over the counter (OTC) in many countries. While NSAIDs are effective in treating inflammation and pain, they can lead to serious side effects such as gastrointestinal bleeding, elevated blood pressure, and increased risk of stroke if not used responsibly. Therefore, it is important to use these medications as advised by a healthcare professional.