Final answer:
The best independent nursing intervention for acute pain is to ask the client about comfort-enhancing methods, as it provides individualized care.
Step-by-step explanation:
The appropriate independent nursing intervention for a client experiencing acute pain is to ask the client what methods enhance comfort. This approach allows for personalized care that considers the client's preferences and experiences with pain management. While administering a nonopioid analgesic, repositioning for comfort, and placing a transdermal patch are interventions for pain relief, these typically require a physician's order and therefore are not considered independent nursing interventions.