Final answer:
Vladek and Anja faced economic, social, political, and personal challenges during the Holocaust that affected every aspect of their existence.
Step-by-step explanation:
The challenges Vladek and Anja faced to stay alive during the Holocaust included a myriad of economic, social, political, and personal challenges. Economically, they had to deal with the loss of property and jobs due to anti-Semitic laws and practices. Socially, they faced the stigmatization and isolation from the non-Jewish community. Politically, they struggled with the oppressive policies of the Nazi regime that systematically aimed to destroy the Jewish population. On a personal level, they had to cope with the psychological trauma of persecution and the constant fear for their own and their families’ lives. These four types of challenges were interwoven and affected every aspect of their existence during the war.