Final answer:
The correct answer to the question is E. None of the above. Christopher Columbus did not land on the North American continent nor did he name indigenous people based on what they called themselves; moreover, the colony of La Isabela does not exist to this day.
Step-by-step explanation:
The multiple-choice question concerning Christopher Columbus and his expeditions has one definite answer. The correct answer is: E. None of the above. To clarify, Columbus first landed on an island in the Bahamas on October 12, 1492. He did not land on the North American continent, specifically present-day Florida, on any of his voyages. The term "Indians" was used by Columbus not because it was what the locals called themselves, but because he believed he had landed in the East Indies and thus thought the inhabitants were Indian. Columbus indeed established a colony on Hispaniola, but it was not La Isabela that exists to present day; La Isabela was abandoned. Instead, the first permanent European settlement was Santo Domingo, which is still inhabited today.
Columbus's belief that he had reached Asia led him to mistakenly call the Taínos "Indios," fostering the misnomer for the native populations of the Americas. And on his third voyage, Columbus explored the coast of Venezuela but did not understand it to be part of the Asian mainland. Therefore, statements A and B are incorrect. The establishment of La Isabela does relate to Columbus, but it doesn't exist to this day, making statement C incorrect as well.