Final answer:
In the early management of a severe head injury, the focus should be on maintaining cerebral perfusion by controlling blood pressure and heart rate to prevent secondary brain injury.
Step-by-step explanation:
The most important principle to follow in the early management of a severe head injury is maintaining adequate cerebral perfusion by ensuring a stable blood pressure and heart rate, preventing secondary brain injury. The Glasgow Coma Scale (GCS) score of 6 indicates a severe injury, necessitating meticulous monitoring and control of intracranial pressure (ICP) and careful management of cerebral perfusion pressure (CPP). Since the patient is already intubated and mechanically ventilated, oxygenation and ventilation are being supported, which is crucial in managing severe head injuries.