Final answer:
Pedigree analysis cannot be experimentally verified, does not consider gene transfer between unrelated species, and is restricted by ethical considerations that prevent controlled breeding experiments in humans.
Step-by-step explanation:
The limitations of pedigree analysis as compared to breeding experiments are significant due to several factors:
- Pedigree analysis cannot be experimentally verified because controlled breeding experiments cannot be ethically conducted on humans to map genetic traits.
- The pedigree model does not account for the possibility of gene transfer between unrelated species, which does not occur in nature and is not relevant for pedigree analysis of human genetic patterns.
- Furthermore, inbreeding in pedigree analysis can lead to an increased incidence of deleterious recessive mutations, as breeders would not allow close relatives to mate to prevent genetic disorders and maintain genetic diversity.
Unlike breeding experiments, pedigree analysis in humans is limited to observation and the use of historical data rather than active manipulation of mating pairs.