Final answer:
Long-term potentiation (LTP) is a persistent strengthening of a synaptic connection. It does not depend on protein synthesis.
Step-by-step explanation:
Long-term potentiation (LTP) is a persistent strengthening of a synaptic connection. It is based on the Hebbian principle, where cells that fire together wire together. LTP involves the insertion of AMPA receptors into the postsynaptic membrane, which enhances the excitatory effect of glutamate released from the presynaptic cell. This strengthening of the synapse is thought to be important for learning and memory. However, long-lasting, long-term potentiation does not depend on protein synthesis.