Final answer:
Statins are drugs that reduce cholesterol levels by inhibiting the enzyme HMG-CoA reductase. They are commonly used to lower cardiovascular risk. Combination treatment of statins and fibrates carries an increased risk of myopathy and rhabdomyolysis.
Step-by-step explanation:
Statins are drugs that reduce cholesterol levels by inhibiting the enzyme HMG-CoA reductase, which synthesizes cholesterol in the body. They are commonly used to lower cardiovascular risk, and dietary modification is usually the initial approach. If triglyceride levels are significantly raised, fibrates may be prescribed instead. Combination treatment of statins and fibrates is highly effective, but it carries an increased risk of myopathy and rhabdomyolysis. Other medications that may be added to statins include ezetimibe, niacin, bile acid sequestrants, and plant sterol-containing products.