Final answer:
To maintain a constant distance between the two strands of a DNA double helix, it is most important that a purine always pairs with a pyrimidine. This pairing follows the specific A-T and C-G matchings, which keeps the width of the helix uniform.
Step-by-step explanation:
The single feature of the structure of a DNA molecule that is most important for ensuring that the two strands of a double helix have a constant distance between them is d. a purine always pairs with a pyrimidine and vice-versa. This principle ensures the uniform width of the DNA helix as the pairing of a purine (adenine or guanine) with a pyrimidine (cytosine or thymine) allows for a consistent arrangement of hydrogen bonds and molecular structure across the entirety of the DNA molecule. The pairings are A-T (adenine-thymine) and C-G (cytosine-guanine) with two and three hydrogen bonds respectively, helping to stabilize the double helix structure.