Final answer:
The false statement is that NHEJ very rarely results in insertion or deletion mutations, as it can indeed lead to such mutations due to its error-prone nature of joining broken DNA ends.
Step-by-step explanation:
The statement "NHEJ very rarely results in insertion or deletion mutations" is the FALSE one in the set of statements provided. Non-homologous end joining (NHEJ) is a repair mechanism used by cells to fix double-strand breaks in DNA, which can occur due to various reasons such as DNA replication errors or environmental factors. When these breaks occur, NHEJ can lead to insertions or deletions because the process involves joining the broken DNA ends directly, without the need for a homologous template. This joining can be error-prone, resulting in insertions or deletions at the site of the repair. NHEJ is indeed important for V(D)J recombination as it contributes to the diversity of the immune system by shuffling gene segments to generate unique antibody genes. Another fact is that NHEJ indeed requires a set of proteins, including Ku proteins, to bind to the DNA ends to initiate the repair process.