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There is NO _______ in chromosome break-induced replication?

a Double-stranded break
b End capture
c Annealing of repeated sequences
d Homology to the strand, which serves as a template for replication

User Shanmugam
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Final answer:

In the context of DNA repair, specifically chromosome break-induced replication, the process does not include the annealing of repeated sequences; instead, it relies on homology searching and binding for repair.

Step-by-step explanation:

The process known as chromosome break-induced replication (BIR) is a pathway for repairing double-stranded breaks in DNA. In BIR, there is no annealing of repeated sequences

Instead, following the break, repair begins when the replication fork reaches the lesion. If a 5'-3' exonuclease trims the template DNA back, RecA proteins then bind to the single-stranded DNA to form a filament that searches for homologous sequences to bind to and initiate repair.

Therefore, the correct answer to the question is 'c Annealing of repeated sequences' because BIR relies on homology to the strand which serves as a template for replication and not annealing of repeated sequences.

User Poyraz Yilmaz
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