Question

Proteins entering the cis Golgi network can do which of the following?

A. They can either move onward through the Golgi stack or be returned to the ER.
B. They can either move backward through the Golgi stack or be sent to the plasma membrane.
C. They are sorted according to whether they are destined for lysosomes or for the cell surface.

Answer 1

Proteins entering the cis Golgi network can move through the Golgi stack, undergoing modifications like glycosylation or phosphorylation, which determine their final destinations, including returning to the ER, lysosomes, or being incorporated into the plasma membrane.

Step-by-step explanation:

Proteins entering the cis Golgi network can do several things. They can either be sorted and move onward through the Golgi stack, or if necessary, be returned to the endoplasmic reticulum (ER). As these proteins pass through the Golgi apparatus, specific modifications such as glycosylation and phosphorylation occur, which can include the addition of carbohydrate groups or phosphate groups. These modifications often serve as a signal sequence that determines the proteins' final destination, such as incorporation into the plasma membrane or organelles, or being directed to lysosomes if tagged with mannose-6-phosphate.