Question

The sequence of the coding strand of a DNA molecule (that is, the DNA strand that contains the codons specifying the protein sequence) is 5'-CGGATGCTTA-3'. What is the sequence of the RNA made from this DNA? Choose one:

A. 5'-AUUCGUAGGC-3'
B. 5'-UAAGCAUCCG-3'
C. 5'-CGGAUGCUUA-3'
D. 5'-GCCUACGAAU-3'
E. 5'-TAAGCATCCG-3'

Answer 1

The RNA sequence made from the DNA strand 5'-CGGATGCTTA-3' is 5'-GCCUACGAAU-3', which is option D in the listed choices. The mRNA is always transcribed in the 5' to 3' direction and Uracil (U) replaces Thymine (T) in RNA.

Step-by-step explanation:

The sequence of the RNA made from the DNA sequence 5'-CGGATGCTTA-3' is determined by matching the complementary bases with the exception that Uracil (U) replaces Thymine (T). Therefore, the mRNA sequence transcribed from this DNA is 5'-GCCUACGAAU-3', which pairs with the given DNA strand starting from the 3' to 5' direction of the DNA strand to create an RNA strand that is in the 5' to 3' direction. This corresponds to option D in the provided choices.

When transcribing from DNA to RNA, the Adenine (A) in the DNA pairs with Uracil (U) in RNA, Thymine (T) with Adenine (A), Cytosine (C) with Guanine (G), and Guanine (G) with Cytosine (C).