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In some bacteria, the short DNA segments identical to DNA of bacteriophage viruses are separated by what?

User Gegenwind
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Final answer:

In bacteriophages, short DNA segments similar to viral DNA are separated by non-viral origin DNA. This is part of the CRISPR immune system in bacteria, providing adaptive immunity by utilizing repeat sequences to recognize and destroy viral DNA. Specialized transduction can transfer bacterial genes via incorrect prophage excision.

Step-by-step explanation:

In bacteriophages, the short DNA segments identical to the DNA of bacteriophage viruses are separated by unique spacers of non-viral origin DNA. This arrangement is part of the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) system, which is a type of bacterial immune system that provides protection against viruses. When a bacteriophage infects a bacterium, part of the phage DNA can be integrated into the CRISPR region of the bacterial genome. These DNA segments from the phage are then flanked by short, identical DNA sequences known as repeats. CRISPR-associated (Cas) proteins use this archived viral DNA to recognize and cut phage DNA during subsequent infections, thus providing adaptive immunity to the bacteria.

Furthermore, during the lysogenic cycle, the viral DNA may become integrated into the bacterial chromosome and persist as a prophage. In some instances, when a prophage is incorrectly excised from the bacterial chromosome, it can take with it small segments of bacterial DNA, which are then packaged into new phage particles. This process, known as specialized transduction, can result in the transfer of bacterial genes between cells.

User Shama
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