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Each different modification of a protein inside the Golgi, happens in the SAME or DIFFERENT compartments?

User GAEfan
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Final answer:

The different modifications of proteins within the Golgi apparatus occur in separate compartments. As molecules pass through these regions, they are modified by specific enzymes, resulting in their proper sorting and routing. Finally, proteins are packaged into vesicles that may either stay inside the cell or be secreted out.

Step-by-step explanation:

The Golgi apparatus is an essential organelle in a cell responsible for the modification, sorting, and packaging of proteins and lipids. Each different modification of a protein inside the Golgi apparatus happens in separate compartments. The Golgi is composed of a series of flattened membranous sacs, each forming a distinct compartment with a specific set of enzymes. This organized structure ensures the progressive modification of molecules as they travel from the cis face to the trans face of the Golgi.

The Golgi apparatus can be logically divided into four main functional regions: the cis-Golgi network, medial-Golgi, endo-Golgi, and trans-Golgi network. As proteins and lipids move from one compartment to the next, they are subjected to specific enzymatic modifications, such as glycosylation (the addition of sugar molecules) and phosphorylation (the addition of phosphate groups). These modifications are vital for the correct routing and function of the molecules once they leave the Golgi apparatus.

Finally, the modified and tagged proteins are packaged into vesicles that bud off from the trans face of the Golgi. These vesicles can either deposit their contents into other parts of the cell or fuse with the plasma membrane to release their contents outside the cell.

User Jeremy McGibbon
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