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A coiled-coil can be formed from α helices that have which of the following attributes? Choose one:

A. the same twist, either right-handed or left-handed
B. many polar, hydrophilic side chains along one side of the helix
C. alternating polar and nonpolar side chains
D. many nonpolar, hydrophobic side chains along one side of the helix

User Sajid Ali
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1 Answer

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Final answer:

A coiled-coil is formed from α helices with many nonpolar, hydrophobic side chains along one side, allowing for hydrophobic interactions that stabilize the structure.

Step-by-step explanation:

A coiled-coil can be formed from α helices that have many nonpolar, hydrophobic side chains along one side of the helix. This is because coiled-coils rely on the hydrophobic interaction among the side chains that protrude out from the α-helix chain to stabilize the structure. In the α-helix, the polypeptide chain adopts a right-handed coil shape, with side chains extending outward. Hydrophobic side chains on one side of the helix can interlock with hydrophobic side chains from another helix in a coiled-coil structure, allowing the two helices to wrap around each other.

User Totowtwo
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