Question

If a point mutation causes the substitution of a single base, what are the potential changes in the resulting amino acid sequence? (check all that apply)

a. no change to the sequence of amino acids
b. a single amino acid change
c. a truncated sequence

Answer 1

A single base substitution in a DNA sequence can result in different effects on the resulting amino acid sequence, including no change, a single amino acid change, or a truncated sequence.

Step-by-step explanation:

A point mutation occurs when a single base in the DNA sequence is substituted with another base. The potential changes in the resulting amino acid sequence depend on the type of point mutation.

A silent mutation occurs when the substituted base does not change the amino acid that is coded for by the mRNA codon. In this case, there will be no change to the sequence of amino acids.

A missense mutation occurs when the substituted base changes the amino acid that is coded for by the mRNA codon. This leads to a single amino acid change in the resulting protein sequence.

A nonsense mutation occurs when the substituted base creates a premature stop codon in the mRNA sequence. This results in a truncated or shortened protein sequence.