Final answer:
Ran dissociates from the nucleus after discharging its cargo through a series of steps involving changes in the affinity of the carrier protein.
Step-by-step explanation:
When the Ran protein has discharged its cargo in the nucleus, it needs to dissociate so that it can carry out its next function. The dissociation of Ran from the nucleus involves several steps:
- Once the cargo is released, the carrier protein undergoes a conformational change that reduces its affinity for the cargo.
- The reduced affinity allows the cargo to be released into the cytoplasm.
- After releasing the cargo, the carrier protein now has a higher affinity for sodium ions.
- This increased affinity for sodium ions triggers the dissociation of the carrier protein from the nucleus.
Overall, the dissociation of Ran from the nucleus is a dynamic process that involves changes in the affinity of the carrier protein for its cargo.