Final answer:
Site-directed mutagenesis is a type of mutagenesis that allows scientists to specify where DNA base changes will occur. The QuickChange process enables site-directed mutagenesis by eliminating the need for digestion with a restriction endonuclease or ligation and reducing the time required for mutagenesis. However, it has limitations in the number of nucleotides that can be modified and the level of amplification it provides.
Step-by-step explanation:
Site-directed mutagenesis (SDM) is a type of mutagenesis that allows scientists to specify exactly where DNA base changes will occur. One process that enables site-directed mutagenesis is the QuickChange process. This process does not require digestion with a restriction endonuclease or ligation, reducing the time required for mutagenesis from a week to a few days. However, it can only modify a few nucleotides at a time and provides less significant amplification of the target DNA sequence compared to conventional PCR.