Final answer:
Smaller cells are more effective at maximizing diffusion due to a higher surface area to volume ratio, which allows for a more efficient exchange of materials with their environment.
Step-by-step explanation:
Cells that are smaller in size or have structures that increase their surface area are the most effective at maximizing diffusion. The efficiency of diffusion in providing nutrients and removing waste is constrained by the surface area to volume ratio. A high surface area relative to volume allows for more efficient exchange of materials. Cells can be small, like many prokaryotes, or have a flattened shape, which increases the surface area relative to volume, facilitating faster diffusion. Large spherical cells have a smaller surface area compared to their volume, which makes diffusion less efficient. Consequently, large cells might develop adaptations that enhance nutrient passage across their cell membrane.