Final answer:
Compounds with long chains of hydrogen and carbon that do not mix with water are classified as lipids, which are distinct from other macromolecules like carbohydrates, proteins, and nucleic acids due to their hydrophobic nature.
Step-by-step explanation:
The compounds that feature long chains of hydrogen and carbon and do not mix with water are known as lipids. These organic compounds are hydrophobic, or water-fearing, which means that they do not interact well with water. Lipids include fats, oils, waxes, phospholipids, and steroids, and are one of the four major classes of biological macromolecules critical for life; the other three are carbohydrates, proteins, and nucleic acids. While carbohydrates are also composed of carbon, hydrogen, and oxygen, they have functional groups that allow them to interact with water, hence they differ from lipids in this regard.