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Typically, when a ligand binds its cognate receptor________

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Final answer:

When a ligand binds to its receptor, conformational changes occur in the receptor's intracellular domain, potentially activating it or its associated proteins. Dimerization of the receptor can also occur as a result of ligand binding.

Step-by-step explanation:

When a ligand binds to its receptor, conformational changes occur in the receptor's intracellular domain. These changes can activate the intracellular domain or its associated proteins. In some cases, ligand binding can also cause dimerization of the receptor, resulting in the formation of a stable complex called a dimer.

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