Question

A loss of function mutant strain of S. cerevisiae for which of the following proteins of the endomembrane system would cause integral membrane proteins to accumulate in the ER?

Option 1: Facilitate Golgi apparatus transport
Option 2: Promote lysosome formation
Option 3: Mediate ER to mitochondria communication
Option 4: Enable smooth ER lipid synthesis

Answer 1

A loss of function mutant strain of S. cerevisiae for Enable smooth ER lipid synthesis protein of the endomembrane system would cause integral membrane proteins to accumulate in the ER.

Step-by-step explanation:

A loss of function mutant strain of S. cerevisiae for Enable smooth ER lipid synthesis protein of the endomembrane system would cause integral membrane proteins to accumulate in the ER. Smooth ER is responsible for synthesizing lipids, including integral membrane proteins, which are embedded in the ER membrane. If the protein responsible for smooth ER lipid synthesis is not functioning properly, the synthesis of these integral membrane proteins would be disrupted, leading to their accumulation in the ER.