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Which of the following acts as an agonist to the cholinergic receptor?

a) Nicotine
b) alpha-Bungarotoxin
c) Norepinephrine
d) Cocaine
e) SSRIs

1 Answer

4 votes

Final answer:

Nicotine acts as an agonist to the cholinergic receptor, specifically binding to and activating the nicotinic receptor, similarly to the neurotransmitter acetylcholine. Therefore correct option is A

Step-by-step explanation:

The act as an agonist to the cholinergic receptor. Of the options provided, nicotine is the substance that acts as an agonist to the cholinergic receptor, specifically the nicotinic receptor. An agonist is a substance that binds to a receptor and produces a similar effect to the endogenous ligand. In this case, nicotine mimics the effect of acetylcholine, which is the natural neurotransmitter for these receptors. It is important to note that nicotine binds to the nicotinic receptor, one of the two main types of cholinergic receptors, rather than the muscarinic receptor.

Alpha-Bungarotoxin is a toxin that blocks nicotinic acetylcholine receptors, so it is not an agonist. Norepinephrine is a neurotransmitter that binds to adrenergic receptors, not cholinergic. Cocaine is a stimulant drug that primarily impacts the reuptake process of neurotransmitters like dopamine but is not an agonist for cholinergic receptors. SSRIs are selective serotonin reuptake inhibitors, which affect serotonin levels but not cholinergic receptors.

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