Final answer:
Notch receptors act as cell-surface receptors and play a crucial role in cell signaling pathways. They have an external ligand-binding domain, a hydrophobic membrane-spanning region, and an intracellular domain. The ligand for Notch receptors is a transmembrane protein called Delta-like or Jagged, and the receptors are located on the cell surface.
Step-by-step explanation:
Notch receptors are cell-surface receptors that act as a key player in cell signaling pathways. They are involved in a variety of cellular processes, such as embryonic development, tissue renewal, and immune response regulation. Notch receptors have an external ligand-binding domain, a hydrophobic membrane-spanning region, and an intracellular domain. The ligand for Notch receptors is a transmembrane protein called Delta-like or Jagged, which binds to the extracellular domain of Notch receptors.
Notch receptors are located on the cell surface, specifically in the plasma membrane. The ligand-binding domain of Notch receptors is exposed on the extracellular side of the membrane, allowing it to interact with the ligand. The intracellular domain of Notch receptors is found inside the cell, and it plays a role in transmitting signals to the nucleus to regulate gene expression.