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Role of Y- tubulin in microtubule nucleation?

User Krugloid
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Final answer:

Gamma-tubulin is fundamental in microtubule nucleation, which is vital for spindle formation during cell division in eukaryotic cells. It organizes the layout of microtubules that distribute chromosomes during mitosis and meiosis and maintains cell structure and intracellular transport.

Step-by-step explanation:

The role of γ-tubulin (gamma-tubulin) in cell division involves its critical function in microtubule nucleation within eukaryotic cells.

Gamma-tubulin is part of the microtubule organizing center (MTOC), which initiates the formation of microtubules.

These microtubules, composed of a- and β-tubulin dimers, rapidly assemble and disassemble to fulfill various cellular functions, notably during mitosis and meiosis.

Specifically, in animal cells, γ-tubulin is found within the centrosome and is essential in forming the spindle apparatus required for the proper segregation of chromatids during cell division.

This organizing center orchestrates the intricate layout of microtubules, which serve as pathways along which genetic material is allocated to daughter cells, ensuring accurate cell division.

Microtubules are also involved in maintaining cell shape, facilitating intracellular transport, and participating in the formation of structures like cilia and flagella.

Given the similarity of γ-tubulin to FtsZ proteins in prokaryotic cells, it is interesting to note the evolutionary conservation of molecular mechanisms that govern cell structure and division across different domains of life.

User Marwan Alsabbagh
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